- 靶点：
- PRX1
- 基因名称：
- PRRX1
- 蛋白名称：
- Paired mesoderm homeobox protein 1
- Human Gene Id：
- 5396
- Human Swiss Prot No：
- P54821
- Mouse Gene Id：
- 18933
- Mouse Swiss Prot No：
- P63013
- Rat Gene Id：
- 266813
- Rat Swiss Prot No：
- P63014
- 免疫原：
- Synthesized peptide derived from PRX1 . at AA range: 30-110
- 特异性：
- PRX1 Polyclonal Antibody detects endogenous levels of PRX1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- PRRX1;PMX1;Paired mesoderm homeobox protein 1;Homeobox protein PHOX1;Paired-related homeobox protein 1;PRX-1
- 实测条带：
- 27kD
- 背景：
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008],
- 功能：
- function:Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,
- 细胞定位：
- Nucleus.
SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis. CELL DEATH AND DIFFERENTIATION Cell Death Differ. 2021 Jun;:1-15 WB Human PANC-1 cell
货号：YT3874
SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis. CELL DEATH AND DIFFERENTIATION Cell Death Differ. 2021 Jun;:1-15 WB Human PANC-1 cell， AsPC-1 cell
货号：YT3874
The rs7911488-T allele promotes the growth and metastasis of colorectal cancer through modulating miR-1307/PRRX1. Cell Death & Disease Cell Death Dis. 2020 Aug;11(8):1-14 WB Human SW480 cell， HCT-116 cell
货号：YT3874
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- 产品图片
.jpg)
- Yang, M., Liu, X., Meng, F. et al. The rs7911488-T allele promotes the growth and metastasis of colorectal cancer through modulating miR-1307/PRRX1. Cell Death Dis 11, 651 (2020).
- Western Blot analysis of various cells using PRX1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
.jpg)
- Western Blot analysis of Jurkat cells using PRX1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
