• 靶点：
• MAZ

• 基因名称：
• MAZ

• 蛋白名称：
• Myc-associated zinc finger protein

• Human Gene Id：
• 4150

• Human Swiss Prot No：
• P56270

• Mouse Swiss Prot No：
• P56671

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208

• 特异性：
• MAZ Polyclonal Antibody detects endogenous levels of MAZ protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• MAZ;ZNF801;Myc-associated zinc finger protein;MAZI;Pur-1;Purine-binding transcription factor;Transcription factor Zif87;ZF87;Zinc finger protein 801

• 实测条带：
• 48kD

• 背景：
• function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,

• 功能：
• function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,

• 细胞定位：
• Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.

• 组织表达：
• Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level). ; [Isoform 1]: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney (PubMed:1502157). Expressed in the joint synovium (PubMed:19583771).

Maimendong and Qianjinweijing Tang (Jin formula) suppresses lung cancer by regulation of miR-149-3p. JOURNAL OF ETHNOPHARMACOLOGY J Ethnopharmacol. 2020 Aug;258:112836 WB Human A549 cell, H1299 cell
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