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WNT7B Polyclonal Antibody

货号：YN0288
应用：WB;ELISA
种属：Human;Mouse

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靶点：
WNT7B

简介：
>>mTOR signaling pathway;>>Wnt signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer

基因名称：
WNT7B

蛋白名称：
Protein Wnt-7b

Human Gene Id：
7477

Human Swiss Prot No：
P56706

Mouse Swiss Prot No：
P28047

免疫原：
Synthesized peptide derived from human protein . at AA range: 110-190

特异性：
WNT7B Polyclonal Antibody detects endogenous levels of protein.

组成：
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

来源：
Polyclonal, Rabbit,IgG

稀释：
WB 1:500-2000 ELISA 1:5000-20000

纯化工艺：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

实测条带：
38kD

背景：
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008],

功能：
function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN.,tissue specificity:Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.,

细胞定位：
Secreted, extracellular space, extracellular matrix . Secreted .

组织表达：
Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.

A Preliminary Study on the Pathogenesis of Colorectal Cancer by Constructing a Hsa-circRNA-0067835-miRNA-mRNA Regulatory Network. OncoTargets and Therapy Oncotargets Ther. 2021; 14: 4645–4658 WB Human 1:1000 SW480 cell
货号：YN0288

Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration AMERICAN JOURNAL OF CHINESE MEDICINE Min Li WB Human,Mouse lung tissues A549 cells
货号：YN0288