IL-1F10 Polyclonal Antibody
- 货号:YT5725
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>Cytokine-cytokine receptor interaction
- 蛋白名称:
- Interleukin-1 family member 10
- 免疫原:
- Synthesized peptide derived from Interleukin-1 family member 10 at AA range: 101-150
- 特异性:
- IL-1F10 Polyclonal Antibody detects endogenous levels of IL-1F10 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- IL1F10;FIL1T;IL1HY2;FKSG75;Interleukin-1 family member 10;IL-1F10;FIL1 theta;Interleukin-1 HY2;IL-1HY2;Interleukin-1 theta;IL-1 theta
- 背景:
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],
- 功能:
- function:Binds soluble IL-1 receptor type 1.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.,
- 细胞定位:
- Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
- 组织表达:
- Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
- Western blot analysis of MOUSE-KIDNEY MOUSE-HEART MOUSE-BRAIN MOUSE-SPLEEN RAT-SPLEEN using IL1F10 antibody. Antibody was diluted at 1:2000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000