Rho GDIγ Polyclonal Antibody
- 货号：YT4082
- 应用：WB;ELISA;IHC
- 种属：Human;Rat;Mouse;
- 简介：
- >>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption
- 蛋白名称：
- Rho GDP-dissociation inhibitor 3
- 免疫原：
- Synthesized peptide derived from Rho GDIγ . at AA range: 110-190
- 特异性：
- Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ARHGDIG;Rho GDP-dissociation inhibitor 3;Rho GDI 3;Rho-GDI gamma
- 背景：
- The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010],
- 功能：
- function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain.,
- 组织表达：
- Primarily expressed in pancreas and brain.
- Western Blot analysis of various cells using Rho GDIγ Polyclonal Antibody
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
