• 靶点：
• NSF

• 简介：
• >>Synaptic vesicle cycle;>>GABAergic synapse;>>Vasopressin-regulated water reabsorption

• 基因名称：
• NSF

• 蛋白名称：
• Vesicle-fusing ATPase

• Human Gene Id：
• 4905

• Human Swiss Prot No：
• P46459

• Mouse Gene Id：
• 18195

• Mouse Swiss Prot No：
• P46460

• Rat Gene Id：
• 60355

• Rat Swiss Prot No：
• Q9QUL6

• 免疫原：
• Synthesized peptide derived from NSF . at AA range: 110-190

• 特异性：
• NSF Polyclonal Antibody detects endogenous levels of NSF protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NSF;Vesicle-fusing ATPase;N-ethylmaleimide-sensitive fusion protein;NEM-sensitive fusion protein;Vesicular-fusion protein NSF

• 实测条带：
• 75kD

• 背景：
• catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,

• 功能：
• catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,

• 细胞定位：
• Cytoplasm.

• 组织表达：
• Brain,Kidney,Lung,

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