MIP-T3 Polyclonal Antibody

    • 货号:YT2768
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • MIP-T3
      • 基因名称:
      • TRAF3IP1
      • 蛋白名称:
      • TRAF3-interacting protein 1
      • Human Swiss Prot No:
      • Q8TDR0
      • Mouse Swiss Prot No:
      • Q149C2
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270
      • 特异性:
      • MIP-T3 Polyclonal Antibody detects endogenous levels of MIP-T3 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • TRAF3IP1;MIPT3;TRAF3-interacting protein 1;Interleukin-13 receptor alpha 1-binding protein 1;Microtubule-interacting protein associated with TRAF3;MIP-T3
      • 实测条带:
      • 78kD
      • 背景:
      • function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,
      • 功能:
      • function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,
      • 细胞定位:
      • Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). .
      • 组织表达:
      • Ubiquitous.
      • 产品图片
      • Immunofluorescence analysis of MCF7 cells, using MIPT3 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MIPT3 Antibody. The picture on the right is blocked with the synthesized peptide.