Gα i-3 Polyclonal Antibody

    • 货号:YT2092
    • 应用:WB;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • GNAI3
      • 简介:
      • >>Rap1 signaling pathway;>>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Sphingolipid signaling pathway;>>Adrenergic signaling in cardiomyocytes;>>Axon guidance;>>Apelin signaling pathway;>>Gap junction;>>Platelet activation;>>Leukocyte transendothelial migration;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Long-term depression;>>Progesterone-mediated oocyte maturation;>>Estrogen signaling pathway;>>Melanogenesis;>>Oxytocin signaling pathway;>>Regulation of lipolysis in adipocytes;>>Renin secretion;>>Relaxin signaling pathway;>>Parathyroid hormone synthesis, secretion and action;>>Cushing syndrome;>>Growth hormone synthesis, secretion and action;>>Gastric acid secretion;>>Parkinson disease;>>Cocaine addiction;>>Morphine addiction;>>Alcoholism;>>Pertussis;>>Chagas disease;>>Toxoplasmosis;>>Human cytomegalovirus infectio
      • 基因名称:
      • GNAI3
      • 蛋白名称:
      • Guanine nucleotide-binding protein G(k) subunit alpha
      • Human Gene Id:
      • 2773
      • Human Swiss Prot No:
      • P08754
      • Mouse Swiss Prot No:
      • Q9DC51
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human GNAI3. AA range:31-80
      • 特异性:
      • Gα i-3 Polyclonal Antibody detects endogenous levels of Gα i-3 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • GNAI3;Guanine nucleotide-binding protein G(k) subunit alpha;G(i) alpha-3
      • 实测条带:
      • 41kD
      • 背景:
      • Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012],
      • 功能:
      • function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1.,
      • 细胞定位:
      • Cytoplasm . Cell membrane ; Lipid-anchor . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. .
      • 组织表达:
      • Liver,
      • 产品图片
      • Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night