BS69 Polyclonal Antibody

    • 货号:YT0537
    • 应用:IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • BS69
      • 基因名称:
      • ZMYND11
      • 蛋白名称:
      • Zinc finger MYND domain-containing protein 11
      • Human Swiss Prot No:
      • Q15326
      • Mouse Swiss Prot No:
      • Q8R5C8
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human ZMY11. AA range:111-160
      • 特异性:
      • BS69 Polyclonal Antibody detects endogenous levels of BS69 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • ZMYND11;BS69;Zinc finger MYND domain-containing protein 11;Adenovirus 5 E1A-binding protein;Protein BS69
      • 分子量:
      • 66kD
      • 背景:
      • The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,
      • 细胞定位:
      • Nucleus . Chromosome . Associates with chromatin and mitotic chromosomes. .
      • 组织表达:
      • Ubiquitous.
      • 产品图片
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ZMY11 Antibody. The picture on the right is blocked with the synthesized peptide.