• 靶点：
• ARHGAP23

• 基因名称：
• ARHGAP23

• 蛋白名称：
• Rho GTPase-activating protein 23

• Human Gene Id：
• 57636

• Human Swiss Prot No：
• Q9P227

• Mouse Swiss Prot No：
• Q69ZH9

• 免疫原：
• Synthesized peptide derived from ARHGAP23 . at AA range: 470-550

• 特异性：
• ARHGAP23 Polyclonal Antibody detects endogenous levels of ARHGAP23 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ARHGAP23;KIAA1501;Rho GTPase-activating protein 23;Rho-type GTPase-activating protein 23

• 分子量：
• 162kD

• 背景：
• The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008],

• 功能：
• function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor.,

• 细胞定位：
• cytosol,extracellular exosome,

• 组织表达：
• Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor.

Pan‑cancer analysis identified ARHGAP23 as a potential biomarker for pancreatic adenocarcinoma Molecular and Clinical Oncology Xiaolong Liu IHC Human 1:200 pancreatic adenocarcinoma (PAAD) tissue
货号：YT0319

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