S100A4 (ABT178R) rabbit mAb
- 货号：YM7274
- 应用：IHC; ELISA
- 种属：Human;
- 蛋白名称：
- Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
- 免疫原：
- Synthesized peptide derived from human S100A4 AA range:50-101
- 特异性：
- This antibody detects endogenous levels of S100A4
- 组成：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源：
- Monoclonal, Rabbit IgG1, Kappa
- 稀释：
- IHC 1:100-500, ELISA 1:5000-20000
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- 18A2;42A;calcium Placental protein;Calvasculin;CAPL;Fibroblast specific protein 1 (FSP1);Fibroblast specific protein 1;Fibroblast specific protein;FSP1;Leukemia multidrug resistance associated protein;Malignant transformation suppression 1 (MTS1);Malignant transformation suppression 1;Metastasin;MTS1;OTTHUMP00000015467;OTTHUMP00000015468;P9KA;PEL98;Placental calcium-binding protein;Protein Mts1;Protein S100 A4;Protein S100-A4;S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog);S100 calcium binding protein A4;S100 calcium-binding protein A4;S100a4;S10A4_HUMAN
- 背景：
- S100 calcium binding protein A4(S100A4) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
- 功能：
- similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.,tissue specificity:Ubiquitously expressed.,
- 细胞定位：
- Nuclear, Cytoplasmic
- 组织表达：
- Ubiquitously expressed.
- Immunohistochemical analysis of paraffin-embedded human Cutaneous squamous carcinoma. 1, Antibody was incubated at 4° overnight. 2, Citrate buffer of pH6.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
- Immunohistochemical analysis of paraffin-embedded human Pancreatic carcinoma. 1, Antibody was incubated at 4° overnight. 2, Citrate buffer of pH6.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
