CD23 (ABT-CD23) mouse mAb (Ready to Use)
- 货号:YM6014R
- 应用:IHC
- 种属:Human
- 简介:
- >>Hematopoietic cell lineage;>>Epstein-Barr virus infection
- 基因名称:
- FCER2 CD23A CLEC4J FCE2 IGEBF
- 蛋白名称:
- Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleav
- 免疫原:
- Synthesized peptide derived from human CD23 AA range: 200-321
- 特异性:
- This antibody detects endogenous levels of human CD23. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Mouse, Monoclonal/IgG1, Kappa
- 纯化工艺:
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- 背景:
- The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
- 功能:
- function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,
- Human appendix tissue was stained with anti-CD23(ABT-CD23) antibody.
- Human diffuse large B-cell lymphoma tissue was stained with Anti-CD23 (ABT-CD23) Antibody
- Human tonsil tissue was stained with anti-CD23(ABT-CD23) antibody.