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IFN-α1 Rabbit pAb

-YT5170

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Main Information
Target

IFN-α1

Host Species

Rabbit

Reactivity

Human

Applications

WB, ELISA

MW

22kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
22kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IFNA1/13. AA range:140-189
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Specificity:
IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
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Gene Name:
IFNA1/IFNA13
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Protein Name:
Interferon alpha-1/13
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Other Name:
IFNA1 ;
IFNA13 ;
Interferon alpha-1/13 ;
IFN-alpha-1/13 ;
Interferon alpha-D ;
LeIF D
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Database Link:
Organism Gene ID SwissProt
Human 3439; P01562;
Mouse P01572;
Background:
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
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Function:
Function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
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Cellular Localization:
Secreted.
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Tissue Expression:
Cerebellum,Leukocyte,
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Research Areas:
>>Cytokine-cytokine receptor interaction ;
>>PI3K-Akt signaling pathway ;
>>Necroptosis ;
>>Toll-like receptor signaling pathway ;
>>NOD-like receptor signaling pathway ;
>>RIG-I-like receptor signaling pathway ;
>>Cytosolic DNA-sensing pathway ;
>>JAK-STAT signaling pathway ;
>>Natural killer cell mediated cytotoxicity ;
>>Alcoholic liver disease ;
>>Tuberculosis ;
>>Hepatitis C ;
>>Hepatitis B ;
>>Measles ;
>>Human cytomegalovirus infection ;
>>Influenza A ;
>>Human papillomavirus infection ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Herpes simplex virus 1 infection ;
>>Epstein-Barr virus infection ;
>>Human immunodeficiency virus 1 infection ;
>>Coronavirus disease - COVID-19 ;
>>Pathways in cancer ;
>>Autoimmune thyroid disease ;
>>Lipid and atherosclerosis
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Catalog: YT5170
Size
Price
Status
Qty.
200μL
$450.00
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100μL
$280.00
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40μL
$150.00
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0

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