Catalog: YN1864
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
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Main Information
Target
CSK22
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
38kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
CSK22 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
38kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
CSK22 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
CSNK2A2 CK2A2
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Protein Name:
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
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Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.,
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.,
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Cellular Localization:
Nucleus . Cytoplasm . Interaction with SIRT6 prevents translocation into the nucleus. .
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Tissue Expression:
Ovary,
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Research Areas:
>>Ribosome biogenesis in eukaryotes ;
>>NF-kappa B signaling pathway ;
>>Mitophagy - animal ;
>>Wnt signaling pathway ;
>>Adherens junction ;
>>Alzheimer disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Measles ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer
>>NF-kappa B signaling pathway ;
>>Mitophagy - animal ;
>>Wnt signaling pathway ;
>>Adherens junction ;
>>Alzheimer disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Measles ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer
show all
Signaling Pathway
Cellular Processes >> Transport and catabolism >> Mitophagy - animal
Cellular Processes >> Cellular community - eukaryotes >> Adherens junction
Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Prion disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Environmental Information Processing >> Signal transduction >> NF-kappa B signaling pathway
Reference Citation({{totalcount}})
Catalog: YN1864
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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