CDC25B

CDC25B ;
CDC25HU2 ;
M-phase inducer phosphatase 2 ;
Dual specificity phosphatase Cdc25B

catalytic activity:Protein tyrosine phosphate + H (2) O = protein tyrosine + phosphate. ,enzyme regulation:Stimulated by B-type cyclins. ,function:Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. ,PTM:Phosphorylated by BRSK1 in vitro. Phosphorylated by CHEK1 , which inhibits the activity of this protein. ,similarity:Belongs to the MPI phosphatase family. ,similarity:Contains 1 rhodanese domain. ,

M phase of mitotic cell cycle , mitotic cell cycle , M phase , nuclear division , oocyte maturation , reproductive developmental process , protein amino acid dephosphorylation , phosphorus metabolic process , phosphate metabolic process , cell cycle , mitosis , meiosis , female meiosis , female meiosis I , gamete generation , germ cell development ,female gamete generation , positive regulation of cell proliferation , oocyte differentiation , dephosphorylation ,regulation of phosphate metabolic process , sexual reproduction , developmental maturation , cell cycle process , cell cycle phase , multicellular organism reproduction , positive regulation of kinase activity , regulation of cell proliferation ,regulation of phosphorylation , positive regulation of catalytic activity , regulation of kinase activity , positive regulation of molecular function , regulation of protein kinase activity , positive regulation of protein kinase activity , organelle fission , cell maturation , oogenesis , oocyte development , reproductive process in a multicellular organism , reproductive cellular process , regulation of phosphorus metabolic process , cell division , meiotic cell cycle , M phase of meiotic cell cycle , regulation of transferase activity , positive regulation of transferase activity ,

Cytoplasm , cytoskeleton , microtubule organizing center , centrosome . Cytoplasm , cytoskeleton , spindle pole .