Catalog: KA3474C
Size
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96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
ZIC1/ZIC2/ZIC3
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Background:
function:May play a role in cerebellar development.,similarity:Belongs to the GLI C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,tissue specificity:CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.,
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Function:
pattern specification process, sensory organ development, behavior, regulation of smoothened signaling pathway, ear morphogenesis, inner ear morphogenesis, ear development, embryonic organ morphogenesis, embryonic organ development, embryonic morphogenesis, inner ear development,
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Cellular Localization:
Nucleus. Cytoplasm . Localizes in the cytoplasm in presence of MDFIC overexpression. .
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Tissue Expression:
CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.
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Signaling Pathway
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Catalog: KA3474C
Size
Price
Status
Qty.
96well
$330.00
In stock
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Add to cart
Collected
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