HBP1

HMG box-containing protein 1 ;
HMG box transcription factor 1 ;
High mobility group box transcription factor 1 ;

function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,

transcription, cell cycle, cell cycle arrest, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, cell cycle process, regulation of transcription,

Nucleus .