Catalog: YV0017
Size
Price
Status
Qty.
100mg
$7,800.00
1 week
0
50mg
$5,600.00
1 week
0
25mg
$3,600.00
1 week
0
5mg
$1,100.00
1 week
0
1mg
$300.00
1 week
0
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Main Information
Target
CD137
Host Species
Rat
Reactivity
Mouse
Applications
In vivo
Detailed Information
Formulation
0.01M PBS, pH 7.4.
Purification
Protein A/G purified from cell culture supernatant.
Purity
Endotoxin level <1 EU/mg. Purity>95% as determined by SDS-PAGE.
Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Concentration
Lot depended
Clonality
Monoclonal
Isotype
IgG2a, kappa
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Antigen&Target Information
Gene Name:
TNFRSF9
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Protein Name:
Tumor necrosis factor receptor superfamily member 9
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Other Name:
TNFRSF9 ;
CD137 ;
ILA ;
Tumor necrosis factor receptor superfamily member 9 ;
4-1BB ligand receptor ;
CDw137 ;
T-cell antigen 4-1BB homolog ;
T-cell antigen ILA ;
CD antigen CD137
CD137 ;
ILA ;
Tumor necrosis factor receptor superfamily member 9 ;
4-1BB ligand receptor ;
CDw137 ;
T-cell antigen 4-1BB homolog ;
T-cell antigen ILA ;
CD antigen CD137
show all
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion , survival , and development of T cells. It can also induce proliferation in peripheral monocytes , enhance T cell apoptosis induced by TCR/CD3 triggered activation , and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq , Jul 2008] ,
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Function:
Function:Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation. ,similarity:Contains 4 TNFR-Cys repeats. ,subunit:Interacts with TRAF1 , TRAF2 and TRAF3. Interacts with LRR-repeat protein 1/LRR-1. ,tissue specificity:Expressed on the surface of activated T-cells. ,
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Cellular Localization:
Membrane; Single-pass type I membrane protein.
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Research Areas:
For research use only.
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YV0017
Size
Price
Status
Qty.
100mg
$7,800.00
1 week
0
50mg
$5,600.00
1 week
0
25mg
$3,600.00
1 week
0
5mg
$1,100.00
1 week
0
1mg
$300.00
1 week
0
Add to cart
Collected
Collect
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