Catalog: YP0325
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Collected
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Main Information
Target
CD32 Phospho Tyr292
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
32kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ITySL
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
32kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307
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Specificity:
Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ITySL
show all
Gene Name:
FCGR2B
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Protein Name:
Low affinity immunoglobulin gamma Fc region receptor II-b
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Other Name:
FCGR2B ;
CD32 ;
FCG2 ;
IGFR2 ;
Low affinity immunoglobulin gamma Fc region receptor II-b ;
IgG Fc receptor II-b ;
CDw32 ;
Fc-gamma RII-b ;
Fc-gamma-RIIb ;
FcRII-b ;
CD antigen CD32
CD32 ;
FCG2 ;
IGFR2 ;
Low affinity immunoglobulin gamma Fc region receptor II-b ;
IgG Fc receptor II-b ;
CDw32 ;
Fc-gamma RII-b ;
Fc-gamma-RIIb ;
FcRII-b ;
CD antigen CD32
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Background:
The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
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Function:
immune response,
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Cellular Localization:
Cell membrane; Single-pass type I membrane protein.
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Tissue Expression:
Research Areas:
>>Phagosome ;
>>Osteoclast differentiation ;
>>B cell receptor signaling pathway ;
>>Fc gamma R-mediated phagocytosis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Measles
>>Osteoclast differentiation ;
>>B cell receptor signaling pathway ;
>>Fc gamma R-mediated phagocytosis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Measles
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YP0325
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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