ATP1AL1 Polyclonal Antibody
- 货号：YT5099
- 应用：WB;ELISA
- 种属：Human;Rat
- 简介：
- >>Oxidative phosphorylation;>>Metabolic pathways
- 蛋白名称：
- Potassium-transporting ATPase alpha chain 2
- 免疫原：
- Synthesized peptide derived from ATP1AL1 . at AA range: 380-460
- 特异性：
- ATP1AL1 Polyclonal Antibody detects endogenous levels of ATP1AL1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ATP12A;ATP1AL1;Potassium-transporting ATPase alpha chain 2;Non-gastric H(+)/K(+) ATPase subunit alpha;Proton pump
- 背景：
- The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
- 功能：
- catalytic activity:ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).,function:Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.,similarity:Belongs to the cation transport ATPase (P-type) family. Type IIC subfamily.,subunit:Composed of two subunits: alpha (catalytic) and beta.,tissue specificity:Found in skin and kidney.,
- 细胞定位：
- Apical cell membrane ; Multi-pass membrane protein .
- 组织表达：
- Expressed in airway epithelial cells (at protein level) (PubMed:29391451). Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
- Western Blot analysis of extracts from rat stomach, using ATP1AL1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
