VRK3 Polyclonal Antibody

    • 货号:YT4893
    • 应用:WB;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • VRK3
      • 基因名称:
      • VRK3
      • 蛋白名称:
      • Inactive serine/threonine-protein kinase VRK3
      • Human Swiss Prot No:
      • Q8IV63
      • Mouse Swiss Prot No:
      • Q8K3G5
      • 免疫原:
      • Synthesized peptide derived from the Internal region of human VRK3.
      • 特异性:
      • VRK3 Polyclonal Antibody detects endogenous levels of VRK3 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • VRK3;Inactive serine/threonine-protein kinase VRK3;Serine/threonine-protein pseudokinase VRK3;Vaccinia-related kinase 3
      • 实测条带:
      • 53kD
      • 背景:
      • vaccinia related kinase 3(VRK3) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],
      • 功能:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probable serine/threonine kinase.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.,similarity:Contains 1 protein kinase domain.,
      • 细胞定位:
      • Nucleus .
      • 组织表达:
      • Brain,Liver,Skin,Testis,Trachea,
      • 产品图片
      • Western Blot analysis of COLO cells using VRK3 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).