Synaptotagmin X Polyclonal Antibody

    • 货号:YT4486
    • 应用:WB;IHC
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Synaptotagmin X
      • 基因名称:
      • SYT10
      • 蛋白名称:
      • Synaptotagmin-10
      • Human Swiss Prot No:
      • Q6XYQ8
      • Mouse Swiss Prot No:
      • Q9R0N4
      • 免疫原:
      • Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460
      • 特异性:
      • Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • SYT10;Synaptotagmin-10;Synaptotagmin X;SytX
      • 实测条带:
      • 55kD
      • 背景:
      • cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
      • 功能:
      • cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
      • 细胞定位:
      • Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .
      • 组织表达:
      • Expressed only in pancreas, lung and kidney.
      • 产品图片
      • Western Blot analysis of 293 cells using Synaptotagmin X Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).