• 靶点：
• S-100A3

• 基因名称：
• S100A3

• 蛋白名称：
• Protein S100-A3

• Human Gene Id：
• 6274

• Human Swiss Prot No：
• P33764

• Mouse Gene Id：
• 20197

• Mouse Swiss Prot No：
• P62818

• Rat Gene Id：
• 114216

• Rat Swiss Prot No：
• P62819

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human S100A3. AA range:26-75

• 特异性：
• S-100A3 Polyclonal Antibody detects endogenous levels of S-100A3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• S100A3;S100E;Protein S100-A3;Protein S-100E;S100 calcium-binding protein A3

• 分子量：
• 12kD

• 实测条带：
• 22kD

• 背景：
• S100 calcium binding protein A3(S100A3) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008],

• 功能：
• function:Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Skin specific.,

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Skin specific, specifically expressed at the inner endocuticle of hair fibers.

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