PLC β3 Polyclonal Antibody

    • 货号:YT3790
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • PLCβ3
      • 简介:
      • >>Inositol phosphate metabolism;>>Metabolic pathways;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Chemokine signaling pathway;>>Phosphatidylinositol signaling system;>>Sphingolipid signaling pathway;>>Phospholipase D signaling pathway;>>Adrenergic signaling in cardiomyocytes;>>Vascular smooth muscle contraction;>>Wnt signaling pathway;>>Apelin signaling pathway;>>Gap junction;>>Platelet activation;>>Neutrophil extracellular trap formation;>>NOD-like receptor signaling pathway;>>Circadian entrainment;>>Long-term potentiation;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>Dopaminergic synapse;>>Long-term depression;>>Taste transduction;>>Inflammatory mediator regulation of TRP channels;>>Insulin secretion;>>GnRH signaling pathway;>>Estrogen signaling pathway;>>Melanogenesis;>>Thyroid hormone synthesis;>>Thyroid hormone signaling pathway;>>Oxytocin signaling pathway;>>Glucagon signaling p
      • 基因名称:
      • PLCB3
      • 蛋白名称:
      • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
      • Human Gene Id:
      • 5331
      • Human Swiss Prot No:
      • Q01970
      • Mouse Swiss Prot No:
      • P51432
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human PLC beta3. AA range:503-552
      • 特异性:
      • PLC β3 Polyclonal Antibody detects endogenous levels of PLC β3 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • PLCB3;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase beta-3;Phosphoinositide phospholipase C-beta-3;Phospholipase C-beta-3;PLC-beta-3
      • 实测条带:
      • 140kD
      • 背景:
      • This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
      • 功能:
      • catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with SHANK2 (By similarity). Interacts with LPAR2.,
      • 细胞定位:
      • Cytoplasm . Membrane . Nucleus . And particulate fractions. .
      • 组织表达:
      • Epithelium,Uterus,

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      货号:YT3790

      • 产品图片
      • Western Blot analysis of various cells using PLC β3 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PLC beta3 Antibody. The picture on the right is blocked with the synthesized peptide.