PHACTR4 Polyclonal Antibody
- 货号:YT3694
- 应用:WB;ELISA;IHC
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Phosphatase and actin regulator 4
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human PHACTR4. AA range:363-412
- 特异性:
- PHACTR4 Polyclonal Antibody detects endogenous levels of PHACTR4 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- PHACTR4;Phosphatase and actin regulator 4
- 背景:
- This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- 功能:
- PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase and actin regulator family.,similarity:Contains 3 RPEL repeats.,subunit:Binds PPP1CA and actin.,
- 细胞定位:
- Cytoplasm . Cell projection, lamellipodium .
- 组织表达:
- Adrenal cortex,Fetal brain,Fetal liver,Skin,Testis,
- Western blot analysis of PHACTR4 Antibody. The lane on the right is blocked with the PHACTR4 peptide.
- Western blot analysis of the lysates from HeLa cells using PHACTR4 antibody.
- Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).