• 靶点：
• Nicalin

• 基因名称：
• NCLN

• 蛋白名称：
• Nicalin

• Human Gene Id：
• 56926

• Human Swiss Prot No：
• Q969V3

• Mouse Gene Id：
• 103425

• Mouse Swiss Prot No：
• Q8VCM8

• Rat Gene Id：
• 314648

• Rat Swiss Prot No：
• Q5XIA1

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523

• 特异性：
• Nicalin Polyclonal Antibody detects endogenous levels of Nicalin protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NCLN;Nicalin;Nicastrin-like protein

• 实测条带：
• 63kD

• 背景：
• function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,

• 功能：
• function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,

• 细胞定位：
• Endoplasmic reticulum membrane ; Single-pass membrane protein .

• 组织表达：
• Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.

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