Eps8L1 Polyclonal Antibody

    • 货号:YT1598
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • Eps8L1
      • 基因名称:
      • EPS8L1
      • 蛋白名称:
      • Epidermal growth factor receptor kinase substrate 8-like protein 1
      • Human Swiss Prot No:
      • Q8TE68
      • Mouse Swiss Prot No:
      • Q8R5F8
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460
      • 特异性:
      • Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • EPS8L1;DRC3;EPS8R1;PP10566;Epidermal growth factor receptor kinase substrate 8-like protein 1;EPS8-like protein 1;Epidermal growth factor receptor pathway substrate 8-related protein 1;EPS8-related protein 1
      • 实测条带:
      • 80kD
      • 背景:
      • This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,
      • 细胞定位:
      • Cytoplasm .
      • 组织表达:
      • Detected in placenta.
      • 产品图片
      • Western Blot analysis of various cells using Eps8L1 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ES8L1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from COLO205 and HT-29 cells, using ES8L1 Antibody. The lane on the right is blocked with the synthesized peptide.