ARHGAP1 Polyclonal Antibody
- 货号:YT0313
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Rho GTPase-activating protein 1
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human RHG1. AA range:189-238
- 特异性:
- ARHGAP1 Polyclonal Antibody detects endogenous levels of ARHGAP1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- ARHGAP1;CDC42GAP;RHOGAP1;Rho GTPase-activating protein 1;CDC42 GTPase-activating protein;GTPase-activating protein rhoOGAP;Rho-related small GTPase protein activator;Rho-type GTPase-activating protein 1;p50-RhoGAP
- 背景:
- This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012],
- 功能:
- function:GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.,similarity:Contains 1 CRAL-TRIO domain.,similarity:Contains 1 Rho-GAP domain.,subunit:Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL.,tissue specificity:Ubiquitous.,
- Immunohistochemistry analysis of paraffin-embedded human heart tissue, using RHG1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from HeLa and HUVEC cells, using RHG1 Antibody. The lane on the right is blocked with the synthesized peptide.