BEST2 Polyclonal Antibody
- 货号：YN5663
- 应用：WB;IHC;IF
- 种属：Mouse;Rat
- 免疫原：
- Synthetic Peptide of BEST2
- 特异性：
- The antibody detects endogenous BEST2 protein.
- 组成：
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-1000 IHC 1:200-500. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Bestrophin-2;Vitelliform macular dystrophy 2-like protein 1
- 背景：
- This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008],
- 功能：
- function:Forms calcium-sensitive chloride channels. May conduct other physiologically significant anions such as bicarbonate.,similarity:Belongs to the bestrophin family.,tissue specificity:Mainly confined to the retinal pigment epithelium and colon.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- 组织表达：
- Mainly confined to the retinal pigment epithelium and colon.
- Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using BEST2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using BEST2 Polyclonal Antibody.
