• 靶点：
• 14-3-3 eta

• 基因名称：
• YWHAH YWHA1

• 蛋白名称：
• 14-3-3 eta

• Human Gene Id：
• 7533

• Human Swiss Prot No：
• Q04917

• Mouse Gene Id：
• 22629

• Mouse Swiss Prot No：
• P68510

• Rat Gene Id：
• 25576

• Rat Swiss Prot No：
• P68511

• 免疫原：
• Synthesized peptide derived from human 14-3-3 eta

• 特异性：
• This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat

• 组成：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• 来源：
• Mouse,monoclonal

• 稀释：
• WB 1:500-2000 IHC 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• 14-3-3 protein eta (Protein AS1)

• 实测条带：
• 28kD

• 功能：
• function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subunit:Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with RGNEF and PCTK1 (By similarity). Weakly interacts with CDKN1B.,tissue specificity:Expressed mainly in the brain and present in other tissues albeit at lower levels.,

• 组织表达：
• Expressed mainly in the brain and present in other tissues albeit at lower levels.

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