PAX-8 Mouse mAb(2B11)

  • 货号:YM3799
  • 应用:WB
  • 种属:Mouse
    • 靶点:
    • Bmi-1
    • 基因名称:
    • PAX8
    • 蛋白名称:
    • PAX-8
    • Human Gene Id:
    • 7849
    • Human Swiss Prot No:
    • Q06710
    • Mouse Swiss Prot No:
    • Q00288
    • 免疫原:
    • Synthesized peptide derived from human PAX-8
    • 特异性:
    • This antibody detects endogenous levels of PAX-8 at Mouse
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Mouse,monoclonal
    • 稀释:
    • WB 1:500-2000
    • 纯化工艺:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Paired box protein Pax-8
    • 实测条带:
    • 48kD
    • 功能:
    • caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,developmental stage:In developing excretory system, during thyroid differentiation and in adult thyroid.,disease:Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2) [MIM:218700]. CHNG2 is a disease characterized by thyroid dysgenesis, the most frequent cause of congenital hypothyroidism, accounting for 85% of case. The thyroid gland can be completely absent (athyreosis), ectopically located and/or severely hypoplastic. Ectopic thyroid gland is the most frequent malformation, with thyroid tissue being found most often at the base of the tongue.,function:Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cell
    • 细胞定位:
    • Nucleus.
    • 组织表达:
    • Expressed in the excretory system, thyroid gland and Wilms tumors.