PAX-5 Mouse mAb(4G6)

  • 货号:YM3798
  • 应用:WB;IHC
  • 种属:Human;Mouse;Rat
    • 靶点:
    • MEK-4
    • 基因名称:
    • PAX5
    • 蛋白名称:
    • PAX-5
    • Human Gene Id:
    • 5079
    • Human Swiss Prot No:
    • Q02548
    • Mouse Swiss Prot No:
    • Q02650
    • 免疫原:
    • Synthesized peptide derived from human PAX-5
    • 特异性:
    • This antibody detects endogenous levels of PAX-5 at Human, Mouse,Rat
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Mouse,monoclonal
    • 稀释:
    • WB 1:500-2000 IHC 1:50-200
    • 纯化工艺:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)
    • 实测条带:
    • 45kD
    • 功能:
    • developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,
    • 细胞定位:
    • Nucleus .