EF-2 Monoclonal Antibody

    • 货号：YM1032
    • 应用：WB
    • 种属：Human;Mouse;Rat
      • 靶点：
      • eEF2
      • 简介：
      • >>AMPK signaling pathway;>>Oxytocin signaling pathway
      • 基因名称：
      • EEF2
      • 蛋白名称：
      • Elongation factor 2
      • Human Gene Id：
      • 1938
      • Human Swiss Prot No：
      • P13639
      • Mouse Swiss Prot No：
      • P58252
      • 免疫原：
      • Purified recombinant human EF-2 protein fragments expressed in E.coli.
      • 特异性：
      • EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein.
      • 组成：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源：
      • Monoclonal, Mouse
      • 稀释：
      • WB 1:1000 - 1:2000. Not yet tested in other applications.
      • 纯化工艺：
      • Affinity purification
      • 浓度：
      • 1 mg/ml
      • 储存：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称：
      • EEF2;EF2;Elongation factor 2;EF-2
      • 分子量：
      • 95kD
      • 背景：
      • This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008],
      • 功能：
      • function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,
      • 细胞定位：
      • Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. .
      • 组织表达：
      • Brain,Cajal-Retzius cell,Epithelium,Hepatocyte,Ovary,Periph
      • 产品图片
      • Western Blot analysis using EF-2 Monoclonal Antibody against HL-60 cell lysate.

      相关报价

      • 货号：
      • YM1032
      • 规格：
      • 50μL / 100μL / 200μL
      • 价格：
      • 2000 / 3200 / 5880
      • 货期：
      • 预计发货时间为
        2024-05-05
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