Fucokinase Monoclonal Antibody
- 货号：YM0288
- 应用：WB;FCM;ELISA
- 种属：Human;Mouse;Rat;Monkey
- 简介：
- >>Fructose and mannose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars
- 免疫原：
- Purified recombinant fragment of human Fucokinase expressed in E. Coli.
- 特异性：
- Fucokinase Monoclonal Antibody detects endogenous levels of Fucokinase protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 稀释：
- WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- Affinity purification
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- FUK;L-fucose kinase;Fucokinase
- 背景：
- fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],
- 功能：
- catalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family.,
- 组织表达：
- Expressed in fibroblasts.
- Western Blot analysis using Fucokinase Monoclonal Antibody against HeLa (1), HepG2 (2), Jurkat (3), A431 (4), HEK293 (5), MCF-7 (6), PC-12 (7), Cos7 (8), and NIH/3T3 (9) cell lysate.
- Flow cytometric analysis of Hela cells using Fucokinase Monoclonal Antibody (green) and negative control (purple).
