Fibulin-2 Monoclonal Antibody
- 货号：YM0271
- 应用：WB;ELISA
- 种属：Human
- 免疫原：
- Purified recombinant fragment of Fibulin-2 (aa180-440) expressed in E. Coli.
- 特异性：
- Fibulin-2 Monoclonal Antibody detects endogenous levels of Fibulin-2 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- Affinity purification
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- FBLN2;Fibulin-2;FIBL-2
- 背景：
- This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
- 功能：
- developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
- 细胞定位：
- Secreted, extracellular space, extracellular matrix.
- 组织表达：
- Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
- Western Blot analysis using Fibulin-2 Monoclonal Antibody against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).
