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Human TIM-1 ELISA Kit
- 货号:KE1258
- 应用:ELISA
- 种属:Human
- 蛋白名称:
- Hepatitis A virus cellular receptor 1
- 特异性:
- Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
- 其他名称:
- HAVCR1;KIM1;TIM1;TIMD1;Hepatitis A virus cellular receptor 1;HAVcr-1;Kidney injury molecule 1;KIM-1;T-cell immunoglobulin and mucin domain-containing protein 1;TIMD-1;T-cell membrane protein 1;TIM-1;TIM
- 背景:
- function:May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.,polymorphism:HHAV seropositivity protects against atopy in individuals with the variants Met-Thr-Thr-Val-Pro-157 ins and Met-Thr-Thr-Thr-Val-Pro-157 ins. Modernisation has led to a reduction in HAV seroprevalence and thus, may be, to an increase of expression of atopy, such as asthma, allergic rhinitis and atopic dermatitis. Allelic variation does not affect HAV-infection rates in Caucasians, Asians and African Americans.,similarity:Belongs to the immunoglobulin superfamily. TIM family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.,
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达:
- Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
- The Human TIM-1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human TIM-1 proteins within the range of 32-2000 pg/ml.