This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
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Function:
Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Function:Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.,similarity:Belongs to the GPN-loop GTPase family.,subunit:Tightly associated with the RNA polymerase II complex. Interacts with XPA.,tissue specificity:Expressed ubiquitously.,
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Cellular Localization:
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .