Catalog: YT7504
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
ACTY
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
41kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of ACTY at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
41kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human ACTY AA range: 29-79
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Specificity:
This antibody detects endogenous levels of ACTY at Human/Mouse
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Gene Name:
ACTR1B CTRN2
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Protein Name:
ACTY
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Background:
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],
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Function:
Function:Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.,similarity:Belongs to the actin family.,similarity:Belongs to the actin family. ARP1 subfamily.,
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Cellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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Research Areas:
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Salmonella infection
>>Huntington disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Salmonella infection
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT7504
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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