Catalog: YT7475
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
ATAD5
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
203kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of ATAD5 at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
203kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human ATAD5 AA range: 1054-1104
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Specificity:
This antibody detects endogenous levels of ATAD5 at Human/Mouse
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Gene Name:
ATAD5 C17orf41 FRAG1
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Protein Name:
ATAD5
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Function:
Function:Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. ATR may stimulate the RAD9A dissociation.,sequence Caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the AAA ATPase family.,subunit:Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents.,
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Cellular Localization:
Nucleus .
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Reference Citation({{totalcount}})
Catalog: YT7475
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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