Catalog: YT7332
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
TYW2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
49kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of TYW2 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
49kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human TYW2 AA range: 11-61
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Specificity:
This antibody detects endogenous levels of TYW2 at Human/Mouse/Rat
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Gene Name:
TRMT12 TRM12 TYW2
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Protein Name:
TYW2
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Database Link:
Background:
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008],
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Function:
Function:Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.,pathway:tRNA modification; wybutosine-tRNA(Phe) biosynthesis.,sequence Caution:Contaminating sequence. Potential poly-A sequence starting in position 371.,sequence Caution:Translation N-terminally shortened.,similarity:Belongs to the RNA methyltransferase trmD family. TYW2 subfamily.,
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Reference Citation({{totalcount}})
Catalog: YT7332
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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