Function:Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.,induction:Up-regulated by basic fibroblast growth factor (bFGF) in gastric cancer cells.,similarity:Belongs to the KCMF1 family.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 ZZ-type zinc finger.,tissue specificity:Spleen, small intestine, ovary, peripheral blood, lung, kidney and pancreas. Expressed at low levels in the thymus, prostate, testis, colon, heart, brain, placenta and liver.,
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Tissue Expression:
Spleen, small intestine, ovary, peripheral blood, lung, kidney and pancreas. Expressed at low levels in the thymus, prostate, testis, colon, heart, brain, placenta and liver.