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Main Information
Target
PEF1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
31kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
31kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PEF1 AA range: 109-159
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Specificity:
This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat
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Gene Name:
PEF1 ABP32 UNQ1845/PRO3573
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Protein Name:
PEF1
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Database Link:
Background:
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010],
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Function:
similarity:Contains 5 EF-hand domains.,subcellular location:Membrane-associated in the presence of Ca(2+).,subunit:Heterodimer; heterodimerizes with PDCD6/ALG2. Dissociates from PDCD6/ALG2 in presence of Ca(2+).,
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Cellular Localization:
Cytoplasm . Endoplasmic reticulum . Membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein . Membrane-associated in the presence of Ca(2+) (PubMed:11278427). Localizes to endoplasmic reticulum exit site (ERES) (By similarity). .
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Catalog: YT6567
Size
Price
Status
Qty.
200μL
$450.00
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100μL
$280.00
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40μL
$150.00
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