Catalog: YT6049
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
Granzyme M
Host Species
Rabbit
Reactivity
Human, Rat
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
The antibody detects endogenous Granzyme M
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthetic peptide from human protein at AA range: 207-256
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Specificity:
The antibody detects endogenous Granzyme M
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Gene Name:
GZMM MET1
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Protein Name:
Granzyme M (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease)
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Other Name:
Granzyme M ;
Met-1 serine protease ;
Hu-Met-1 ;
Met-ase ;
Natural killer cell granular protease ;
Met-1 serine protease ;
Hu-Met-1 ;
Met-ase ;
Natural killer cell granular protease ;
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Background:
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
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Function:
Function:Cleaves peptide substrates after methionine, leucine, and norleucine.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Granules of large granular lymphocytes.,
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Cellular Localization:
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YT6049
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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