Catalog: YT5710
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
CD88
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, ELISA
MW
39kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
39kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human C5AR1. AA range:1-50
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Specificity:
CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.
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Gene Name:
C5AR1
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Protein Name:
C5a anaphylatoxin chemotactic receptor
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Other Name:
C5AR1 ;
C5AR ;
C5R1 ;
C5a anaphylatoxin chemotactic receptor ;
C5a-R ;
C5aR ;
CD88
C5AR ;
C5R1 ;
C5a anaphylatoxin chemotactic receptor ;
C5a-R ;
C5aR ;
CD88
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Background:
function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Function:
Function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .
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Tissue Expression:
Brain,
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Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Complement and coagulation cascades ;
>>Neutrophil extracellular trap formation ;
>>Alcoholic liver disease ;
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
>>Complement and coagulation cascades ;
>>Neutrophil extracellular trap formation ;
>>Alcoholic liver disease ;
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT5710
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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