Catalog: YT5567
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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0
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Main Information
Target
IGFBP1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
28kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
IGFBP1 Polyclonal Antibody detects endogenous levels of IGFBP1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
28kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP1. AA range:91-140
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Specificity:
IGFBP1 Polyclonal Antibody detects endogenous levels of IGFBP1 protein.
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Gene Name:
IGFBP1
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Protein Name:
Insulin-like growth factor-binding protein 1
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Other Name:
IGFBP1 ;
IBP1 ;
Insulin-like growth factor-binding protein 1 ;
IBP-1 ;
IGF-binding protein 1 ;
IGFBP-1 ;
Placental protein 12 ;
PP12
IBP1 ;
Insulin-like growth factor-binding protein 1 ;
IBP-1 ;
IGF-binding protein 1 ;
IGFBP-1 ;
Placental protein 12 ;
PP12
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Database Link:
Background:
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008],
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Function:
Function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.,PTM:Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,subunit:Binds equally well IGF1 and IGF2.,
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Cellular Localization:
Secreted.
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YT5567
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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