Catalog: YT4894
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
v-SNARE Vti1a
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
23kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
v-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
23kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human VTI1A. AA range:31-80
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Specificity:
v-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein.
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Gene Name:
VTI1A
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Protein Name:
Vesicle transport through interaction with t-SNAREs homolog 1A
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Other Name:
VTI1A ;
Vesicle transport through interaction with t-SNAREs homolog 1A ;
Vesicle transport v-SNARE protein Vti1-like 2 ;
Vti1-rp2
Vesicle transport through interaction with t-SNAREs homolog 1A ;
Vesicle transport v-SNARE protein Vti1-like 2 ;
Vti1-rp2
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Database Link:
Background:
The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
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Function:
Function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,
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Cellular Localization:
Cytoplasmic vesicle . Golgi apparatus membrane ; Single-pass type IV membrane protein .
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Tissue Expression:
Lung,
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Research Areas:
>>SNARE interactions in vesicular transport
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Reference Citation({{totalcount}})
Catalog: YT4894
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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