Catalog: YT4767
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
TSSK 4
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
40kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TSSK 4 Polyclonal Antibody detects endogenous levels of TSSK 4 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
40kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human TSSK4. AA range:211-260
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Specificity:
TSSK 4 Polyclonal Antibody detects endogenous levels of TSSK 4 protein.
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Gene Name:
TSSK4
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Protein Name:
Testis-specific serine/threonine-protein kinase 4
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Other Name:
TSSK4 ;
C14orf20 ;
STK22E ;
TSSK5 ;
Testis-specific serine/threonine-protein kinase 4 ;
TSK-4 ;
TSSK-4 ;
Testis-specific kinase 4 ;
Serine/threonine-protein kinase 22E
C14orf20 ;
STK22E ;
TSSK5 ;
Testis-specific serine/threonine-protein kinase 4 ;
TSK-4 ;
TSSK-4 ;
Testis-specific kinase 4 ;
Serine/threonine-protein kinase 22E
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Background:
This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-197, potentially by autophosphorylation.,Function:May be involved in a signaling pathway during male germ cell development or mature sperm function (By similarity). Phosphorylates CREB1 on Ser-133 and stimulates downstream signaling.,PTM:Autophosphorylated (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed only in the testis.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome . Cell projection, cilium, flagellum . In spermatozoa, present in the sperm head and in the flagellum. .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YT4767
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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