Catalog: YT4758
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
TSC-22
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
16kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TSC-22 Polyclonal Antibody detects endogenous levels of TSC-22 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
16kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human TSC22D1. AA range:71-120
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Specificity:
TSC-22 Polyclonal Antibody detects endogenous levels of TSC-22 protein.
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Gene Name:
TSC22D1
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Protein Name:
TSC22 domain family protein 1
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Other Name:
TSC22D1 ;
KIAA1994 ;
TGFB1I4 ;
TSC22 ;
hucep-2 ;
TSC22 domain family protein 1 ;
Cerebral protein 2 ;
Regulatory protein TSC-22 ;
TGFB-stimulated clone 22 homolog ;
Transforming growth factor beta-1-induced transcript 4 protein
KIAA1994 ;
TGFB1I4 ;
TSC22 ;
hucep-2 ;
TSC22 domain family protein 1 ;
Cerebral protein 2 ;
Regulatory protein TSC-22 ;
TGFB-stimulated clone 22 homolog ;
Transforming growth factor beta-1-induced transcript 4 protein
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Database Link:
Background:
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],
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Function:
Function:Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.,induction:In aortic endothelial cells, induced by cytokines, including TGFB.,similarity:Belongs to the TSC-22/Dip/Bun family.,subunit:Homodimer or heterodimer. Can form an heterodimer with TSC22D4.,tissue specificity:Widely expressed in fetal and adult tissues.,
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Cellular Localization:
Cytoplasm . Nucleus .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YT4758
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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