WB 1:500-2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
24kD
MW(Observed)
17kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human TP53INP2. AA range:1-50
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Specificity:
TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.
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Gene Name:
TP53INP2
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Protein Name:
Tumor protein p53-inducible nuclear protein 2
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Other Name:
TP53INP2 ;
C20orf110 ;
DOR ;
PINH ;
Tumor protein p53-inducible nuclear protein 2 ;
Diabetes and obesity-regulated gene ;
p53-inducible protein U ;
PIG-U
tumor protein p53 inducible nuclear protein 2(TP53INP2) Homo sapiens The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016],
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Cellular Localization:
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.