Catalog: YT4652
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
TIEG-1/2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
53kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TIEG-1/2 Polyclonal Antibody detects endogenous levels of TIEG-1/2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
53kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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TIEG-1/2 Rabbit pAb
YT4652
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Total TIEG-1/2 Cell-Based Colorimetric ELISA Kit
KA3703C
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RS0001
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human KLF10/11. AA range:391-440
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Specificity:
TIEG-1/2 Polyclonal Antibody detects endogenous levels of TIEG-1/2 protein.
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Gene Name:
KLF10/11
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Protein Name:
Krueppel-like factor 10/11
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Other Name:
KLF10 ;
TIEG ;
TIEG1 ;
Krueppel-like factor 10 ;
EGR-alpha ;
Transforming growth factor-beta-inducible early growth response protein 1 ;
TGFB-inducible early growth response protein 1 ;
TIEG-1 ;
KLF11 ;
FKLF ;
TIEG2 ;
Krueppel-like factor 11 ;
Transfor
TIEG ;
TIEG1 ;
Krueppel-like factor 10 ;
EGR-alpha ;
Transforming growth factor-beta-inducible early growth response protein 1 ;
TGFB-inducible early growth response protein 1 ;
TIEG-1 ;
KLF11 ;
FKLF ;
TIEG2 ;
Krueppel-like factor 11 ;
Transfor
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Database Link:
Background:
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
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Function:
Function:Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.,induction:By TGF-beta.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Epithelium,Eye,Placenta,
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Reference Citation({{totalcount}})
Catalog: YT4652
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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